BDBM393277 5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N-[(2- methyl-1,3-thiazol-5- yl)methyl]-6- (trifluoromethyl)pyrazine- 2-carboxamide::US9963434, Table 12.220

SMILES Cc1ncc(CNC(=O)c2cnc(CNS(=O)(=O)c3ccc(F)c(Cl)c3)c(n2)C(F)(F)F)s1

InChI Key InChIKey=FPXNFVMIOBJMDT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393277   

TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Luc Therapeutics

US Patent
LigandPNGBDBM393277(5-(3-chloro-4- fluorobenzenesulfon- amidomethyl)-N...)
Affinity DataIC50:  169nMAssay Description:Cell Culture and plating: HEK293 cells expressing NR1/NR2A (Chantest, Cleveland, Ohio) were grown to 70-80% confluency as an adherent monolayer in st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent