BDBM393394 US9963444, Example 95
SMILES COc1cccc(c1)-c1ccc(COC2(C)CN(C2)C#N)cc1
InChI Key InChIKey=XYFPPQFRZROGKN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 393394
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
US Patent
Northeastern University
US Patent
Affinity DataIC50: 55nMAssay Description:In order to have an assay method more conducive to high-throughput screening than those published for measuring the NAE hydrolyzing activity of NAAA,...More data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of recombinant human hexaHis-tagged MGL expressed in Escherichia coli BL21 (DE3) using fluorogenic AHMMCE as substrate preincubated for 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.360nMAssay Description:Inhibition of recombinant human FAAH expressed in Escherichia coli using fluorogenic AAMCA as substrate by fluorimetric assayMore data for this Ligand-Target Pair
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Northeastern University
US Patent
Northeastern University
US Patent
Affinity DataIC50: 1.80nMAssay Description:Inhibition of activated human NAAA using fluorogenic PAMCA and N-4-methylcoumarin as substrate incubated for 90 mins by fluorescence based assayMore data for this Ligand-Target Pair