BDBM393419 N-[5-[(2S,5R,6S)-5-amino-6- fluoro-oxepan-2-yl]-1-methyl- pyrazol-4-yl]-2-(2,3- dihydrobenzofuran-5- yl)thiazole-4-carboxamide::US9963446, Example 104

SMILES Cn1ncc(NC(=O)c2csc(n2)-c2ccc3OCCc3c2)c1[C@@H]1CC[C@@H](N)[C@H](F)CO1

InChI Key InChIKey=VBMFRJUOAHRISC-CLCXKQKWSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393419   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM393419(N-[5-[(2S,5R,6S)-5-amino-6- fluoro-oxepan-2-yl]-1-...)
Affinity DataKi:  0.104nMAssay Description:Determination of the Pim kinase activity of a Formula I compound is possible by a number of direct and indirect detection methods. Certain exemplary ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent