BDBM393553 US9969687, Compound 224

SMILES Cc1ccc(N2C(=O)c3c(C2=O)c(NS(=O)(=O)c2ccc(cc2)C(C)(C)C)ccc3Cl)c(C)n1

InChI Key InChIKey=CGXQAMBLIMZJIO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 393553   

TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

Curated by ChEMBL
LigandPNGBDBM393553(US9969687, Compound 224)
Affinity DataKi:  5nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intracellular calcium level preincubate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

Curated by ChEMBL
LigandPNGBDBM393553(US9969687, Compound 224)
Affinity DataKi:  6nMAssay Description:Antagonist activity at CCR9A receptor (unknown origin) overexpressed in human MOLT4 cells assessed as inhibition of CCL25-induced increase in intrace...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

Curated by ChEMBL
LigandPNGBDBM393553(US9969687, Compound 224)
Affinity DataKi:  6nMAssay Description:A calcium flux assay was used to determine the ability of the compounds to interfere with the binding between CCR9 and its chemokine ligand (TECK) in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-C chemokine receptor type 9(Homo sapiens (Human))
Norgine

Curated by ChEMBL
LigandPNGBDBM393553(US9969687, Compound 224)
Affinity DataKi: >300nMAssay Description:Antagonist activity at CCR9 receptor in human MOLT4 cells assessed as inhibition of CCl25-mediated cell migration preincubated for 30 mins followed C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed