BDBM393795 US10597367, Example 84::US9969726, Example 84

SMILES OC(=O)c1cc(F)cc(c1)-c1ccc(cc1)-c1nc(cc(n1)C(F)(F)F)-c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=RNBIYNWGOXACMB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 393795   

TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393795(US10597367, Example 84 | US9969726, Example 84)
Affinity DataEC50:  2.79E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 5(Rattus norvegicus (Rat))
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM393795(US10597367, Example 84 | US9969726, Example 84)
Affinity DataEC50:  4.91E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 2(Rattus norvegicus)
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393795(US10597367, Example 84 | US9969726, Example 84)
Affinity DataEC50:  2.79E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetabotropic glutamate receptor 3(Rattus norvegicus (Rat))
Sanford-Burnham Medical Research Institute

US Patent
LigandPNGBDBM393795(US10597367, Example 84 | US9969726, Example 84)
Affinity DataEC50:  4.91E+3nMAssay Description:Human Embryonic Kidney (HEK-293) cell lines co-expressing rat mGlu receptors 2, 3, 4, 6, 7 or 8 and G protein-coupled inwardly-rectifying potassium (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent