BDBM393924 US9969749, Example 1-18::trans-N'-[6-(1-ethyl-1H- pyrazol-4-yl)quinazolin- 4-yl]-N,N- dimethylcyclohexane- 1,4-diamine

SMILES CCN\C=C(/C=N)c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N(C)C)c2c1

InChI Key InChIKey=ZJDROGMFLVIHGO-VLLPKFMFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393924   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393924(US9969749, Example 1-18 | trans-N'-[6-(1-ethyl-1H-...)
Affinity DataIC50:  92nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent