BDBM393947 US9969749, Example 1-40::trans-N'-{6-[5-(2- methoxyethoxy)pyridin- 3-yl]quinazolin-4-yl}- N,N- dimethylcyclohexane- 1,4-diamine

SMILES COCCOc1cncc(c1)-c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N(C)C)c2c1

InChI Key InChIKey=LCWPQWBNOUNINY-MXVIHJGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393947   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393947(US9969749, Example 1-40 | trans-N'-{6-[5-(2- metho...)
Affinity DataIC50:  83nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent