BDBM393950 2-{[5-(4-{[trans-4- (dimethylamino)cyclohexyl] amino}quinazolin-6- yl)pyrimidin-2- yl]amino}ethanol::US9969749, Example 1-43

SMILES CN(C)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)-c1cnc(NCCO)nc1

InChI Key InChIKey=JVICIVSUGGITLS-IYARVYRRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393950   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393950(2-{[5-(4-{[trans-4- (dimethylamino)cyclohexyl] ami...)
Affinity DataIC50:  25nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent