BDBM393954 N-[trans-4-(morpholin- 4-yl)cyclohexyl]-6- (pyrimidin-5- yl)quinazolin-4-amine::US9969749, Example 1-47

SMILES C1CN(CCO1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)-c1cncnc1

InChI Key InChIKey=OBBRVAGUUCKENI-WGSAOQKQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393954   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393954(N-[trans-4-(morpholin- 4-yl)cyclohexyl]-6- (pyrimi...)
Affinity DataIC50:  3nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent