BDBM393985 5-methyl-N-(trans-4- morpholin-4- ylcyclohexyl)-6- pyrimidin-5- ylquinazolin-4-amine::US9969749, Example 1-76

SMILES Cc1c(ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c12)-c1cncnc1

InChI Key InChIKey=MVKNDKYACXJWNK-WGSAOQKQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 393985   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM393985(5-methyl-N-(trans-4- morpholin-4- ylcyclohexyl)-6-...)
Affinity DataIC50:  223nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent