BDBM394025 6-(1-methyl-1H-pyrazol- 5-yl)-N-(trans-4- morpholin-4- ylcyclohexyl)quinazolin- 4-amine::US9969749, Example 2-13

SMILES Cn1nccc1-c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N3CCOCC3)c2c1

InChI Key InChIKey=ADPXVECAENPWJL-IYARVYRRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394025   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394025(6-(1-methyl-1H-pyrazol- 5-yl)-N-(trans-4- morpholi...)
Affinity DataIC50:  324nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent