BDBM394055 5-(4-{[trans-4-(4- methylpiperazin-1- yl)cyclohexyl]amino} quinazolin-6-yl)pyridin-3-ol::US9969749, Example 5-5

SMILES CN1CCN(CC1)[C@H]1CC[C@@H](CC1)Nc1ncnc2ccc(cc12)-c1cncc(O)c1

InChI Key InChIKey=SRAZUQWIUMTCKQ-MXVIHJGJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 394055   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394055(5-(4-{[trans-4-(4- methylpiperazin-1- yl)cyclohexy...)
Affinity DataIC50:  1nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent