BDBM394158 3-[(4-{3-[(1S)- 1-{5-[5-chloro- 2-(1H- tetrazol-1- yl)phenyl]-1- oxidopyridin- 2-yl}-2- phenylethyl] phenyl} piperidin- 1- yl)carbonyl] cyclobutanone::US9975874, Example 32
SMILES Clc1ccc(c(c1)-c1ccc([nH+]c1)[C@@H](Cc1ccccc1)c1cccc(c1)C1CCN(CC1)C(=O)C1CC(=O)C1)-n1cnnn1
InChI Key InChIKey=QUSNISKZXOJQDZ-YTTGMZPUSA-O
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 394158
Affinity DataIC50: 324nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Affinity DataIC50: 11.1nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair