BDBM394159 5-[5-chloro-2- (1H-tetrazol- 1-yl)phenyl]- 2-[(1S)-1-{3- [1-(3- methoxy- propanoyl) piperidin- 4-yl]phenyl}- 2- phenylethyl] pyridine 1- oxide::US9975874, Example 33
SMILES COCCC(=O)N1CCC(CC1)c1cccc(c1)[C@H](Cc1ccccc1)c1ccc(c[nH+]1)-c1cc(Cl)ccc1-n1cnnn1
InChI Key InChIKey=BLTANBDUBMLEEC-HKBQPEDESA-O
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 394159
Affinity DataIC50: 376nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Kallikrein can be determined using a relevant purified serine protease, a...More data for this Ligand-Target Pair
Affinity DataIC50: 11.2nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 150 mM NaCl, 5 mM CaCl2, and 0.1% PEG 8000 (polyethylene glycol; JT Ba...More data for this Ligand-Target Pair