BDBM394187 US9975876, 9::methyl 2-{[3R,6R)-1-{[5-fluoro-2- (5-methyl-1,2,4-oxadiazol-3- yl)phenyl]carbonyl}-6- methylpiperidin-3-yl]oxy}-4- methoxypyridine-3-carboxylate

SMILES COC(=O)c1c(OC)ccnc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1cc(F)ccc1-c1noc(C)n1

InChI Key InChIKey=FESPCMXZVOAYNW-CZUORRHYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394187   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394187(US9975876, 9 | methyl 2-{[3R,6R)-1-{[5-fluoro-2- (...)
Affinity DataIC50:  1.50E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394187(US9975876, 9 | methyl 2-{[3R,6R)-1-{[5-fluoro-2- (...)
Affinity DataIC50:  36.7nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent