BDBM394198 US9975876, 22::methyl 2-({(3R,6R)-1-[(3-fluoro-2- pyrimidin-2-ylphenyl)carbonyl]-6- methylpiperidin-3-yl}oxy)-4- methoxypyridine-3-carboxylate

SMILES COC(=O)c1c(OC)ccnc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1cccc(F)c1-c1ncccn1

InChI Key InChIKey=IRPHYIAMNHJXNM-HZPDHXFCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394198   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394198(US9975876, 22 | methyl 2-({(3R,6R)-1-[(3-fluoro-2-...)
Affinity DataIC50:  3.78E+3nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394198(US9975876, 22 | methyl 2-({(3R,6R)-1-[(3-fluoro-2-...)
Affinity DataIC50:  117nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent