BDBM394209 US9975876, 34::methyl 2-methoxy-6-({(3R,6R)-6- methyl-1-[(2-pyrimidin-2- ylthiophen-3-yl)carbonyl]piperidin- 3-yl}oxy)benzoate

SMILES COC(=O)c1c(OC)cccc1O[C@@H]1CC[C@@H](C)N(C1)C(=O)c1ccsc1-c1ncccn1

InChI Key InChIKey=GPHPAXLGRLDEPG-HZPDHXFCSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 394209   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394209(US9975876, 34 | methyl 2-methoxy-6-({(3R,6R)-6- me...)
Affinity DataIC50: >1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM394209(US9975876, 34 | methyl 2-methoxy-6-({(3R,6R)-6- me...)
Affinity DataIC50:  42nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent