BDBM394376 N-(3-(2-(difluoromethoxy)-5-(3-(3- hydroxy-1-methylazetidin-3- yl)phenoxy)phenyl)-1-(2- (dimethylamino)-2-oxoethyl)-1H- pyrazol-4-yl)pyrazolo[1,5- a]pyrimidine-3-carboxamide::US10307426, Example 18
SMILES CN(C)C(=O)Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cc(Oc2cccc(c2)C2(O)CN(C)C2)ccc1OC(F)F
InChI Key InChIKey=FRBLFLTVXJPVBV-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 394376
Affinity DataKi: 1.56nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Affinity DataKi: 3.18nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair