BDBM394575 2-(6-amino-5-(2-::US10308614, Example 178

SMILES CC(COc1cc(nnc1N)-c1ccccc1O)c1ccccc1

InChI Key InChIKey=VVYATDRFTFUUGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 394575   

TargetTranscription activator BRG1 [1448-1575](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM394575(2-(6-amino-5-(2- | US10308614, Example 178)
Affinity DataIC50:  12.2nMAssay Description:His-BRG1 (A1448-S1575; Swiss Prot P51532; mhhhhhhgslvpr\gsAEKLSPNPP NLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNH KYRSLNDLEKDVMLLCQNA...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProtein polybromo-1 [645-766](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM394575(2-(6-amino-5-(2- | US10308614, Example 178)
Affinity DataIC50:  5.30nMAssay Description:Histidine-Flag-PB1-BD5 Bromodomain645-766 (S645-D766; Swiss Prot Q86U86; mhhhhhhasdykddddkgslvpr\gsSGISPKKSKYMTPMQQKLNEVYEAVKNYTDKRGRRLSAI FLRLPSRSEL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM394575(2-(6-amino-5-(2- | US10308614, Example 178)
Affinity DataIC50:  7.20nMAssay Description:Histidine epitope tagged BRM (Isoform 2) Bromodomain1377-1486 (S1377-Q1486; Swiss Prot P51531-2; mhhhhhhgslvpr\gsSPNPPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQL...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent