BDBM394657 (3-methylphenyl){2-[(pyridin-3-ylmethyl)amino]pyrimidin-5-yl}methanone::US10308615, Example 14
SMILES Cc1cccc(c1)C(=O)c1cnc(NCc2cccnc2)nc1
InChI Key InChIKey=QUFWCLLJSUHQDF-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 394657
Affinity DataIC50: 47.8nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant N-terminal FLAG/His6-tagged human vanin-1 expressed in CHO cells using Pantetheine-7-amino-4-trifluoromethykournarin as sub...More data for this Ligand-Target Pair
Affinity DataIC50: <13nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Affinity DataIC50: 31.5nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair