BDBM395249 US10308629, Example 11::rel-(4aR,7aS)-6-Methyl-3-(phenylamino)-2-(pyridin-4-yl)-1,4a,5,6,7a,8-hexahydropyrrolo[3,4-f]indole-4,7-dione

SMILES COC(=O)C1CC(O)=C(C(=S)Nc2ccccc2)C(=O)C1

InChI Key InChIKey=YJLNQXRRJGTRBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395249   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395249(US10308629, Example 11 | rel-(4aR,7aS)-6-Methyl-3-...)
Affinity DataIC50:  19nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent