BDBM395263 N-{4-[(7RS)-3-Anilino-7-methyl-4-oxo-1,4,5,6,7,8-hexahydrocyclohepta[b]pyrrol-2-yl]pyridin-2-yl}acetamide::US10308629, Example 25::US10308629, Example 38

SMILES CC1CCC(=O)c2c(C1)[nH]c(c2Nc1ccccc1)-c1ccnc(NC(C)=O)c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395263   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395263(N-{4-[(7RS)-3-Anilino-7-methyl-4-oxo-1,4,5,6,7,8-h...)
Affinity DataIC50:  27nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395263(N-{4-[(7RS)-3-Anilino-7-methyl-4-oxo-1,4,5,6,7,8-h...)
Affinity DataIC50:  7nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent