BDBM395306 6-(2-Hydroxypropan-2-yl)-N-[6-(2-hydroxypropan-2-yl)-2-(4,4,4-trifluorobutyl)-2H-indazol-5-yl]pyridine-2-carboxamide::US10308634, Example 21::US10793545, Example 21

SMILES CC(C)(O)c1cccc(n1)C(=O)Nc1cc2cn(CCCC(F)(F)F)nc2cc1C(C)(C)O

InChI Key InChIKey=RYFZQBGEZMHRHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395306   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395306(6-(2-Hydroxypropan-2-yl)-N-[6-(2-hydroxypropan-2-y...)
Affinity DataIC50:  117nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM395306(6-(2-Hydroxypropan-2-yl)-N-[6-(2-hydroxypropan-2-y...)
Affinity DataIC50:  117nMAssay Description:For the assay, 11 different concentrations in the range from 20 μM to 0.073 nM were prepared from a 2 mM DMSO solution of the test substance. 50...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent