BDBM395331 US10308636, Example 8

SMILES COC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)-c1ccc(cn1)-c1nc(cn1COCC[Si](C)(C)C)-c1ccccc1

InChI Key InChIKey=FMFPJYJLRCUCLK-MCZWQBSQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395331   

TargetDiacylglycerol O-acyltransferase 1(Homo sapiens (Human))
Mitsubishi Tanabe Pharma

US Patent
LigandPNGBDBM395331(US10308636, Example 8)
Affinity DataIC50:  6.10nMAssay Description:As a buffer used for the enzymatic reaction of DGAT1, 100 mM Tris-HCl (pH7.4), 200 mM Sucrose, and 20 mM MgCl2, 0.125% Bovin Serum Albumin (BSA) were...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent