BDBM395561 2-((R)-1-((7-cyano-2-(3'-(3- (((R)-3-hydroxypyrrolidin-1- yl)methyl)-1,7-naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl-3- yl)benzo[d]oxazol-5- yl)methyl)pyrrolidin-3- yl)acetic acid::US10308644, Example 173::US10800768, Example 173::US11339149, Example 173

SMILES Cc1c(Nc2nccc3cc(CN4CC[C@@H](O)C4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@H](CC(O)=O)C4)cc(C#N)c3o2)c1C

InChI Key InChIKey=GQXMXAMBQGUKMQ-WXGMZPBLSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395561   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395561(2-((R)-1-((7-cyano-2-(3'-(3- (((R)-3-hydroxypyrrol...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395561(2-((R)-1-((7-cyano-2-(3'-(3- (((R)-3-hydroxypyrrol...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395561(2-((R)-1-((7-cyano-2-(3'-(3- (((R)-3-hydroxypyrrol...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent