BDBM395626 1-((7-cyano-2-(3'- (5-(2-(dimethyl- amino)acetyl)-5,6- dihydro-4H- pyrrolo[3,4-d]- thiazol-2-yl)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]- oxazol-5-yl)- methyl)piperidine- 4-carboxylic acid::US10308644, Example 236::US10800768, Example 236::US11339149, Example 236

SMILES CN(C)CC(=O)N1Cc2nc(sc2C1)-c1cccc(c1C)-c1cccc(-c2nc3cc(CN4CCC(CC4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=LGQIPQPNZSBINF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395626   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395626(1-((7-cyano-2-(3'- (5-(2-(dimethyl- amino)acetyl)-...)
Affinity DataIC50: <10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395626(1-((7-cyano-2-(3'- (5-(2-(dimethyl- amino)acetyl)-...)
Affinity DataIC50: <10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM395626(1-((7-cyano-2-(3'- (5-(2-(dimethyl- amino)acetyl)-...)
Affinity DataIC50:  3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent