BDBM395935 US10308660, Example 11
SMILES Cn1c(nc(N)c(Sc2cccc(OC(F)(F)F)c2)c1=O)N1CCC(C)(CN)CC1
InChI Key InChIKey=ZKJQYGMEKKOBKM-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 395935
Affinity DataIC50: 441nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair