BDBM395955 US10308660, Example 31

SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(N)c(Sc3cccc(N)c3C(F)(F)F)c(=O)n2C)[C@@H]1N

InChI Key InChIKey=FWLRJXKKWWAIIU-MEDUHNTESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395955   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM395955(US10308660, Example 31)
Affinity DataIC50:  20nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent