BDBM396020 5-((2-amino-3-chloropyridin-4-yl)thio)-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-3,6-dimethylpyrimidin-4(3H)-one::US10308660, Example 121
SMILES C[C@@H]1OCC2(CCN(CC2)c2nc(C)c(Sc3ccnc(N)c3Cl)c(=O)n2C)[C@@H]1N
InChI Key InChIKey=QFRRGTFNDYLUIL-BLLLJJGKSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 396020
Affinity DataIC50: 60nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair