BDBM396079 US10308660, Example 181

SMILES COc1ccccc1-c1c(N)nc(N2CCC3(CO[C@@H](C)[C@H]3N)CC2)n(C)c1=O

InChI Key InChIKey=YRNRWTLQVVVTQD-SUMWQHHRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396079   

TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM396079(US10308660, Example 181)
Affinity DataIC50:  840nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent