BDBM396313 US9980929, Example 11

SMILES COc1ccc(OC(CC(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F)c2cccc(Cl)c2)cc1

InChI Key InChIKey=FMFHGQUCTDRENV-ZEJIAQGSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396313   

TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM396313(US9980929, Example 11)
Affinity DataIC50:  55nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent