BDBM396353 US9980929, Example 55

SMILES CC(C)[C@H](NC(=O)[C@@H](NC(=O)C(Cc1ccc(Cl)c(Cl)c1)Oc1ccc(Cl)c(Cl)c1)c1ccccc1)C(=O)C(F)(F)F

InChI Key InChIKey=XYDINTUMKRPKMZ-DJHGOXGWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396353   

TargetSerine protease HTRA1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM396353(US9980929, Example 55)
Affinity DataIC50:  1.18nMAssay Description:Enzyme activity is measured by observing the increase in fluorescence intensity caused by cleavage of a peptide substrate containing a fluorophore, w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent