BDBM396392 3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-azetidine::US9981909, Example 17

SMILES Fc1cccc(COc2ccc(Br)cc2OC2CNC2)c1

InChI Key InChIKey=NBNIWNSSNWVBTD-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 396392   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396392(3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-azetidi...)
Affinity DataKi:  4nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396392(3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-azetidi...)
Affinity DataKi:  10nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396392(3-[5-Bromo-2-(3-fluoro-benzyloxy)-phenoxy]-azetidi...)
Affinity DataKi:  39nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent