BDBM396466 (R)-3-(2-Benzyloxy-4-chloro-phenoxy)-1-methyl-pyrrolidine::US9981909, Example 91

SMILES CN1CC[C@H](C1)Oc1ccc(Cl)cc1OCc1ccccc1

InChI Key InChIKey=DDEKZOKOHWNMEQ-MRXNPFEDSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 396466   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396466((R)-3-(2-Benzyloxy-4-chloro-phenoxy)-1-methyl-pyrr...)
Affinity DataKi:  5nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396466((R)-3-(2-Benzyloxy-4-chloro-phenoxy)-1-methyl-pyrr...)
Affinity DataKi:  50nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396466((R)-3-(2-Benzyloxy-4-chloro-phenoxy)-1-methyl-pyrr...)
Affinity DataKi:  120nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396466((R)-3-(2-Benzyloxy-4-chloro-phenoxy)-1-methyl-pyrr...)
Affinity DataKi:  500nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent