BDBM396566 3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy]-azetidine::US9981909, Example 191

SMILES Fc1cccc(CCOc2ccc(Cl)cc2OC2CNC2)c1

InChI Key InChIKey=GUQORBGSQWLBDR-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 396566   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396566(3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy...)
Affinity DataKi:  7nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396566(3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy...)
Affinity DataKi:  8nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396566(3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy...)
Affinity DataKi:  8nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396566(3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy...)
Affinity DataKi:  11nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396566(3-[5-Chloro-2-[2-(3-fluoro-phenyl)-ethoxy]-phenoxy...)
Affinity DataKi:  53nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent