BDBM396590 3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetidine::US9981909, Example 215

SMILES CC1(CNC1)Oc1cc(Br)ccc1OCCc1ccccc1

InChI Key InChIKey=BJCYJONYVDPPGZ-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 396590   

Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetid...)
Affinity DataKi:  6nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 7(Rattus norvegicus (rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetid...)
Affinity DataKi:  11nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetid...)
Affinity DataKi:  17nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetid...)
Affinity DataKi:  26nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM396590(3-(5-Bromo-2-phenethyloxy-phenoxy)-3-methyl-azetid...)
Affinity DataKi:  44nMAssay Description:Receptor binding was performed using membrane fractions prepared from the HEK-293 cell line recombinantly expressing rat 5-HT7 receptors (NCBI access...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent