BDBM396709 US9981925, Compound 43

SMILES CNC[C@@H](Nc1ncnc2c(nccc12)C(N)=O)c1ccc(c(c1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=CBTQJPOBHJHENE-CYBMUJFWSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 396709   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM396709(US9981925, Compound 43)
Affinity DataIC50: <25nMAssay Description:In order to measure AKT inhibition in the Caliper Life Sciences LC3000, a TTP Mosquito liquid handling instrument was used to place 125 nl of the app...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM396709(US9981925, Compound 43)
Affinity DataIC50: <25nMAssay Description:p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent