BDBM396854 US9981950, Example 61
SMILES Fc1cc(ccc1Cl)-n1cc(Cn2ccnc2C2CC2)nn1
InChI Key InChIKey=BJBDOPNIPHEBTL-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 396854
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
Affinity DataIC50: 31.7nMAssay Description:Cells were split 2-3 times weekly between 1:3 and 1:4. For binding assays and membrane preparations the cell culture medium was removed, cells were w...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Janssen Pharmaceuticals
US Patent
Janssen Pharmaceuticals
US Patent
Affinity DataIC50: 31.7nMAssay Description:Male Wistar rats (180 to 200 g) were killed by suffocation in a CO2 chamber for two minutes. Whole brains without cerebellum were removed and dissect...More data for this Ligand-Target Pair