BDBM397086 2-(2-{5-[(2-Ethoxypyridin-3-yl)carbonyl]hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-5-methyl-1,3-oxazol-4-yl)propan-2-ol::US9987255, 2

SMILES CCOc1ncccc1C(=O)N1CC2CN(CC2C1)c1nc(c(C)o1)C(C)(C)O

InChI Key InChIKey=ZSVBZMPQZSPQPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397086   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397086(2-(2-{5-[(2-Ethoxypyridin-3-yl)carbonyl]hexahydrop...)
Affinity DataIC50:  1.00E+4nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM397086(2-(2-{5-[(2-Ethoxypyridin-3-yl)carbonyl]hexahydrop...)
Affinity DataIC50:  545nMAssay Description:In a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent