BDBM397571 2-[1-(ethylsulfonyl)-3-(4-{[(1R,2S)-2-phenylcyclopropyl]amino}piperidin-1-yl)azetidin-3-yl]-N,N-dimethylacetamide::US10676457, Example 70::US11155532, Example 70::US9994546, Example 70

SMILES CCS(=O)(=O)N1CC(CC(=O)N(C)C)(C1)N1CCC(CC1)N[C@@H]1CC1c1ccccc1

InChI Key InChIKey=OSXJNKWWLVSYHK-BPGUCPLFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 397571   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM397571(2-[1-(ethylsulfonyl)-3-(4-{[(1R,2S)-2-phenylcyclop...)
Affinity DataIC50:  30nMAssay Description:LANCE LSD1/KDM1A demethylase assay 10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM397571(2-[1-(ethylsulfonyl)-3-(4-{[(1R,2S)-2-phenylcyclop...)
Affinity DataIC50: <100nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM397571(2-[1-(ethylsulfonyl)-3-(4-{[(1R,2S)-2-phenylcyclop...)
Affinity DataIC50: <100nMAssay Description:LANCE LSD1/KDM1A demethylase assay—10 μL of 1 nM LSD-1 enzyme (ENZO BML-SE544-0050) in the assay buffer (50 mM Tris, pH 7.5, 0.01% Tween-20, 25 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent