BDBM397948 US10604536, Compound 20::US9994590, Compound 20

SMILES Cn1c(nc2c1ccc1ncccc21)C1CC1c1ccc2ccccc2n1

InChI Key InChIKey=IYIRZPZMLNDEFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397948   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397948(US10604536, Compound 20 | US9994590, Compound 20)
Affinity DataIC50:  300nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397948(US10604536, Compound 20 | US9994590, Compound 20)
Affinity DataIC50:  300nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent