BDBM397970 US10604536, Compound 42::US9994590, Compound 42

SMILES COc1cccn2c(C)c(nc12)C1CCC1c1nc2c(C)ncc(C)n2n1

InChI Key InChIKey=AJIQTIGIEJEWCF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 397970   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397970(US10604536, Compound 42 | US9994590, Compound 42)
Affinity DataIC50: >500nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharamaceuticals

US Patent
LigandPNGBDBM397970(US10604536, Compound 42 | US9994590, Compound 42)
Affinity DataIC50: >500nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent