BDBM397981 US10604536, Compound 54::US9994590, Compound 53
SMILES [H][C@]1(C[C@@]1([H])c1nc2c(OC)cc(C)cn2c1C)c1nc2c(C)ncc(C)n2n1
InChI Key InChIKey=CNUDDRJDGHKKKW-HUUCEWRRSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 397981
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals
US Patent
Sunovion Pharmaceuticals
US Patent
Affinity DataIC50: 300nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals
US Patent
Sunovion Pharmaceuticals
US Patent
Affinity DataIC50: 55nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals
US Patent
Sunovion Pharmaceuticals
US Patent
Affinity DataIC50: 300nMAssay Description:The compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 enzyme expressed in...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Sunovion Pharmaceuticals
US Patent
Sunovion Pharmaceuticals
US Patent
Affinity DataIC50: 55nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair