BDBM398051 US10322118, Entry 9
SMILES Oc1ccc(Oc2ccccc2)cc1
InChI Key InChIKey=ZSBDGXGICLIJGD-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 398051
Affinity DataKi: 6.20E+4nMAssay Description:Binding affinity to recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as inhibitory constant incubated for 30 mins by f...More data for this Ligand-Target Pair
Affinity DataKd: 3.70E+4nMAssay Description:Binding affinity to BAX (unknown origin) assessed as dissociation constant by ITC analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 5.93E+5nMAssay Description:Agonist activity at recombinant human LXRbeta-LBD expressed in Escherichia coli BL21 (DE3) assessed as peptide D22 recruitment fluorescence polarizat...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:The first step in characterizing the two compounds identified by high throughput screening was to verify that the inhibition was reproducible using f...More data for this Ligand-Target Pair