BDBM398141 4-Chloro-1-oxetan-3-yl-1H-indole-3-carboxylic acid ((1S,2S,4S)-2-bicyclo[2.2.1]hept-5-en-2-yl-ethyl)-amide::US10323000, Compound 75::US10676433, Compound 75
SMILES Clc1cccc2n(cc(C(=O)NCC[C@@H]3C[C@H]4C[C@@H]3C=C4)c12)C1COC1
InChI Key InChIKey=FINHVAFWUMJYKD-QLFBSQMISA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 398141
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair