BDBM398226 Preparations of 4-chloro-N-((4,4-difluoro-1-hydroxycyclohexyl) methyl)-1-((tetrahydro-2H-pyran-2-yl)methyl)-1H-indole-3-carboxamide::US10323000, Compound 166
SMILES OC1(CNC(=O)c2cn(CC3CCCCO3)c3cccc(Cl)c23)CCC(F)(F)CC1
InChI Key InChIKey=ZCTFEKFFUUCYKD-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 398226
Affinity DataIC50: 55nMAssay Description:The activation of P2X7 by ATP leads to a fast transient activation of cells resulting in influx of Ca2+ followed by conversion of pro-IL-1β to a...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Agonist-induced pore formation was determined by measuring cellular uptake of YO PRO fluorescence dye in HEK293 transfected with human P2X7 receptor....More data for this Ligand-Target Pair