BDBM398271 US10323016, Example 8
SMILES COc1ccc(cc1OC)N(C)c1cnc(SCc2c(F)cc(cc2F)C#CC[NH+](C)C)n1-c1ccc(F)cc1
InChI Key InChIKey=VAEQURLTVRZWMG-UHFFFAOYSA-O
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 398271
TargetG-protein coupled bile acid receptor 1(Mus musculus)
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 17nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
Universite De Lille 2 Droit Et Sante
US Patent
Universite De Lille 2 Droit Et Sante
US Patent
Affinity DataEC50: 260nMAssay Description:In the following tables TGR5 activation by compounds and subsequent increase in intracellular cAMP were evaluated using a luciferase reporter gene as...More data for this Ligand-Target Pair