BDBM398610 1-((3S,4R)-4-(3,5-difluoro- phenyl)-1-(2-methoxyethyl) pyrrolidin-3-yl)-3-(2- phenyl-4,6-dihydro-2H- furo[3,4-c]pyrazol-3-yl) urea::US10323022, Example 88

SMILES COCCN1C[C@@H](NC(=O)Nc2c3COCc3nn2-c2ccccc2)[C@@H](C1)c1cc(F)cc(F)c1

InChI Key InChIKey=CLXDOHGEALNGGG-RBBKRZOGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398610   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398610(1-((3S,4R)-4-(3,5-difluoro- phenyl)-1-(2-methoxyet...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent