BDBM398619 1-((3S,4R)-1-(2-methoxy- ethyl)-4-phenylpyrrolidin- 3-yl)-3-(1-methyl-3- (pyridin-4-yl)-1H-pyrazol- 5-yl)urea::US10323022, Example 96

SMILES COCCN1C[C@@H](NC(=O)Nc2cc(nn2C)-c2ccncc2)[C@@H](C1)c1ccccc1

InChI Key InChIKey=WLSLWSPVFYGBIX-PZJWPPBQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398619   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398619(1-((3S,4R)-1-(2-methoxy- ethyl)-4-phenylpyrrolidin...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent