BDBM398644 US10323022, Example 121::methyl 4-(5-(3-((3S,4R)- 4-(3,4-difluorophenyl)- 1-(2-methoxyethyl) pyrrolidin-3-yl)ureido)- 1-methyl-1H-pyrazol- 3-yl)benzoate

SMILES COCCN1C[C@@H](NC(=O)Nc2cc(nn2C)-c2ccc(cc2)C(=O)OC)[C@@H](C1)c1ccc(F)c(F)c1

InChI Key InChIKey=LRWQEDHRXWFZLL-WMZHIEFXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 398644   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM398644(US10323022, Example 121 | methyl 4-(5-(3-((3S,4R)-...)
Affinity DataIC50: <100nMAssay Description:Trk enzymatic selectivity was assessed using Omnia Kinase Assay reagents from Invitrogen Corp. Enzyme (TrkA from Invitrogen Corp.) and test compound ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent